Slow recruitment rate

This is a phase III randomized multi-center study of equivalence comparing the radiological follow-up for patients benefiting from the correction of the esthetical relapse of the preservative treatment by fatty transfer compared with a simple supervision.

It is planned that 440 patients participate in this study which plans to compare 2 groups of patients: a group of patients which will benefit from the surgical treatment by transfer of fatty tissue and a group of patients under simple supervision.

follow-up consultations are planned in 10 in 45 days post-surgery then at 3 months, 6 months, 12 months and 5 years to look for the expected unwanted effects in relation with the surgery but also to estimate the impact of the fatty transfer on the rate of local and\or from a distance relapse.

During these consultations, the surgeon and the patient will also estimate the cosmetic result of the surgery thanks to a questionnaire of cosmetic evaluation and to standardized photos.

Inclusion Criteria:

• History of breast cancer treated by conservative surgery .
• Normal inclusion radiological assessment normal (ACR1 or ACR2)
• Moderate Deformations (Type I and II of the classification of Clough).
• Delay with regard to the end of the radiotherapy superior or equal to one-year-old.
• Moderated radio-dystrophies (< Grade 2 of the score LENT/SOMA).
• Signature of the informed consent
• Patient benefiting from social security
• Patient of more than 18 years old

Exclusion Criteria:

• Abnormal radiological assessment (ACR3, ACR4 or ACR5)
• Absence of fatty excess .
• radio surgical relapses with vast fibroses of the breast (> Grade 2 of the score LENT/SOMA).
• Patient under 18 years old.
• administrative difficulties: impossibility to provide enlightened information to the patient, the refusal to sign the consent .
• pregnant women or breast feeding women
• patient under legal guardianship
• bilateral breast cancer regardless histologic type.