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To assess whether a non-invasive cardiac output monitor can follow heart function in children during treatments in the hospital. To establish a normal reference for children who are well and awake.
The aim of the study is to evaluate the ability of a new FDA-approved non-invasive Electrical Velocimetry (EV) cardiac monitor called AESCULON (Cardiotronic Inc, La Jolla CA) to detect and trend hemodynamic changes in hospitalized ambulatory pediatric patients during recovery from acute illness. We postulate that if the cardiac monitor can trend hemodynamic changes in hypertensive patients whose mean arterial pressure (MAP) decreases to normal levels, or hypotensive patients whose MAP increases to normal levels over several days, it may improve our understanding of different disease processes and allow us to improve care. We also seek to establish normative data for different measures provided by the AESCULON monitor - specifically cardiac output (CO) and systemic vascular resistance (SVR), which are the prime determinants of MAP.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elevated Mean Arterial Blood Pressure | Mean arterial pressure greater than 1 standard deviation above the mean based on age | ||
| Decrease Mean Arterial Blood Pressure | Mean arterial pressure greater than 1 standard deviation below the mean based on age | ||
| Normal Mean Arterial Blood Pressure | Mean arterial pressure within the standard deviation of the mean based on age |
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| Measure | Description | Time Frame |
|---|---|---|
| To document trends in cardiac output (CO) and systemic vascular resistance (SVR) in subjects undergoing systematic changes in mean arterial pressure (MAP) and to assess intra-individual variability for those with normal blood pressure | During hospitalization until discharge |
| Measure | Description | Time Frame |
|---|---|---|
| To establish age relevant hemodynamic norms as measured by the electrical velocimetry (EV) cardiac monitor for trend parameters | Measurements obtain on day of discharge |
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Inclusion Criteria:
Exclusion Criteria:
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Hospitalized children
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Children's Hospital Boston | Boston | Massachusetts | 02115 | United States |
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