The main purpose of this study is to assess the safety, tolerability and PK of AZD9742 after single IV doses.

Inclusion Criteria:

• Provision of signed and dated, written informed consent prior to any study specific procedures.
• Clinically normal physical findings and laboratory values as judged by the investigator with normal ECG.
• Healthy male and female volunteers. Females must be of non childbearing potential.

Exclusion Criteria:

• Clinically significant illness or clinically relevant trauma, as judged by the investigator, within 4 weeks of the first administration of the Investigational Product
• History of any disease or condition known to interfere with the absorption, distribution, metabolism or excretion of drugs