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| Name | Class |
|---|---|
| American Diabetes Association | OTHER |
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The purpose of the proposed study is to determine whether the amount children sleep is associated with changes in hormones, hunger, motivation to eat, and food intake. Fifty children 8-11 years old who sleep 9-10 hours per night will be enrolled for a 3-week study. For 1 week each, children will be asked to sleep their typical amount, increase their sleep by 1-½ hours, and decrease their sleep by 1-½ hours. Half of the children will be asked to increase their sleep first and half to decrease their sleep first. During each week, the following will be gathered: sleep duration (measured by actigraphy, which is a small device that measures sleep), levels of hormones measured through blood draws, self-reported hunger and appetite, food intake (measured by 3 days of 24-hour recall), how motivated children are to eat (measured using a computer activity), and child height and weight. We believe that when children sleep less they will show changes in hormones associated with hunger and appetite, report being hungrier, be more motivated to eat, and eat more food.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Children with Insufficient Sleep | Children who sleep approximately 9-10 hours/night |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Increase Sleep | Behavioral | Children are asked to increase their sleep by approximately 1 1/2 hours/night for 1 week. |
|
| Measure | Description | Time Frame |
|---|---|---|
| absolute reinforcing value of food as compared to sedentary activities | after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration |
| Measure | Description | Time Frame |
|---|---|---|
| plasma levels of leptin and ghrelin | after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration | |
| caloric intake | after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration |
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Inclusion Criteria:
Exclusion Criteria:
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Children ages 8-11 years old recruited from Southeastern New England.
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| Name | Affiliation | Role |
|---|---|---|
| Chantelle N Hart, PhD | The Miriam Hospital/Alpert Medical School of Brown University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Weight Control and Diabetes Research Center | Providence | Rhode Island | 02903 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35390756 | Derived | Hart CN, Spaeth AM, Egleston BL, Carskadon MA, Raynor HA, Jelalian E, Owens JA, Considine RV, Wing RR. Effect of changes in children's bedtime and sleep period on targeted eating behaviors and timing of caloric intake. Eat Behav. 2022 Apr;45:101629. doi: 10.1016/j.eatbeh.2022.101629. Epub 2022 Mar 26. | |
| 24190680 | Derived |
| Label | URL |
|---|---|
| Weight Control and Diabetes Research Center | View source |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D005247 | Feeding Behavior |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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2 ml of whole blood drawn at each of 3 assessments
| Decrease Sleep | Behavioral | Children are asked to decrease their sleep by approximately 1 1/2 hours/night. |
|
| levels of physical activity | after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration |
| subjective ratings of hunger and appetite | after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration |
| Hart CN, Carskadon MA, Considine RV, Fava JL, Lawton J, Raynor HA, Jelalian E, Owens J, Wing R. Changes in children's sleep duration on food intake, weight, and leptin. Pediatrics. 2013 Dec;132(6):e1473-80. doi: 10.1542/peds.2013-1274. Epub 2013 Nov 4. |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001522 | Behavior, Animal |
| D001519 | Behavior |