Study of Positive Airway Pressure in Preeclampsia to Reduce Blood Pressure

Use of PAP in Women With Pre-eclampsia

The purpose of this study is to identify whether sleep-disordered breathing - as measured by overnight polysomnography - is associated with pre-eclampsia and to determine whether use of positive airway pressure can improve nocturnal blood pressure.

Initial enrollment began with only women with a pre-existing diagnosis of pre-eclampsia. Part way through the study, IRB granted approval to expand recruitment to include other hypertensive diagnoses. So, in effect, a more accurate post hoc title would be Study of Positive Airway Pressure to Reduce Blood Pressure in Hypertensive Pregnancies.

Inclusion Criteria:

• Women with preeclampsia who receive care at the University of Michigan Hospitals
• No current use of PAP therapy.
• Willing and able to provide informed consent.

Exclusion Criteria:

• Current PAP therapy
• Any medical reason why PAP therapy may not be suitable (e.g., in patients with recent head trauma).
• Cognitively impaired and unable to understand informed consent.