The purpose of this study is to identify whether sleep-disordered breathing - as measured by overnight polysomnography - is associated with pre-eclampsia and to determine whether use of positive airway pressure can improve nocturnal blood pressure.

Initial enrollment began with only women with a pre-existing diagnosis of pre-eclampsia. Part way through the study, IRB granted approval to expand recruitment to include other hypertensive diagnoses. So, in effect, a more accurate post hoc title would be Study of Positive Airway Pressure to Reduce Blood Pressure in Hypertensive Pregnancies.

Inclusion Criteria:

• Women with preeclampsia who receive care at the University of Michigan Hospitals
• No current use of PAP therapy.
• Willing and able to provide informed consent.

Exclusion Criteria:

• Current PAP therapy
• Any medical reason why PAP therapy may not be suitable (e.g., in patients with recent head trauma).
• Cognitively impaired and unable to understand informed consent.

These data are for those who initiated APAP only and do not include the standard of care arm as they did not have nocturnal blood pressure

from start of intervention until 30 days after intervention (generally 30 days after delivery)

NOTE: All cause mortality table reflects maternal death only - as babies were not participants.

Inpatient hospitalizations were not collected as data for adverse event collection (and therefore are not included in Serious Adverse Events reporting) because this was a study of high risk pregnancies, so recruitment came from inpatient candidates as well as from the community.

For non-serious adverse events: study did not collect ordinary aspects of pregnancy such as nausea.

These tables represent full basic analysis of all the participants enrolled without adjustment for confounding variables. Future publications will present more complex subsequent analyses.