The purpose of this study is to compare the central corneal thickness measurement in patients with exfoliation syndrome, exfoliative glaucoma, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma.

To compare the central corneal thickness measurement in patients with exfoliation, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma. Prospective study in progress. Randomly selected patients undergo a comprehensive ophthalmic exam which includes 2 separate pachymetry measurements in 2 different examinations at the same time of the day (10:00 am) with 3 different pachymeters. The values obtained are correlated with a number of other glaucoma parameters. A thinner cornea may represent a specific attribute and an additional risk factor for patients with exfoliation. Evaluation of corneal thickness is an important exam in the management of patients with exfoliation.

Inclusion Criteria:

• Exfoliation material on pupil
• Intraocular pressure below 21 mm Hg without glaucomatous damage
• Intraocular pressure above 21 mm Hg without glaucomatous damage
• Raised intraocular pressure with glaucomatous damage

Exclusion Criteria:

• Corneal disorders
• History of trauma
• Evidence of corneal abnormality that may influence IOP
• Contact lens use
• Corneal surgery

individuals with and without exfoliation