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| Name | Class |
|---|---|
| Fundação de Amparo à Pesquisa do Estado de São Paulo | OTHER_GOV |
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The purpose of this study was to investigate if salivary flow rate is important to maintain adequate oral functions.
Hyposalivation may damage oral functions. Therefore, the aim of this study was to evaluate whether patients under hyposalivation present damaged mastication and speech. Forty subjects composed 2 groups: Control (C) and hyposalivation (H). Masticatory performance (MP) was carried out using artificial material and a 10-sieve method. Mandibular movements during speech were obtained using a 3D jaw-tracking device. Neither mastication nor speech have been impaired by low salivary flow rate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Subjects with normal salivary flow rate | ||
| Hyposalivation | Subjects presenting low salivary flow rate as a side effect of systemic isotretinoin therapy. |
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Inclusion Criteria:
Exclusion Criteria:
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Forty subjects were selected (20 male and 20 female) among people seeking for dental treatment, students and staff of Piracicaba Dental School.Saliva collection was performed for all subjects, and indivuduals with normal salivary flow rate composed the control group. Hyposalivation group group, otherwise, was composed by subjects taking 0.5-0.7 mg/kg/day for at least one month prescribed by a dermatologist.
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| Name | Affiliation | Role |
|---|---|---|
| Renata CM Rodrigues Garcia, PhD | Piracicaba Dental School | Study Chair |
| Alrair A Del Bel Cury, PhD | Piracicaba Dental School | Study Director |
| Simone G Farias Gomes, MS | Piracicaba Dental School | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Piracicaba Dental School | Piracicaba | São Paulo | 13414-903 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 1399047 | Background | Saliva: its role in health and disease. Working Group 10 of the Commission on Oral Health, Research and Epidemiology (CORE). Int Dent J. 1992 Aug;42(4 Suppl 2):287-304. No abstract available. | |
| 16933461 | Background | Bianchini EM, de Andrade CR. A model of mandibular movements during speech: normative pilot study for the Brazilian Portuguese language. Cranio. 2006 Jul;24(3):197-206. doi: 10.1179/crn.2006.032. |
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| ID | Term |
|---|---|
| D003142 | Communication |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| 1778098 | Result | Liedberg B, Owall B. Masticatory ability in experimentally induced xerostomia. Dysphagia. 1991;6(4):211-3. doi: 10.1007/BF02493529. |
| 15125589 | Result | Ishijima T, Koshino H, Hirai T, Takasaki H. The relationship between salivary secretion rate and masticatory efficiency. J Oral Rehabil. 2004 Jan;31(1):3-6. doi: 10.1111/j.1365-2842.2004.01033.x. |