Role of Indoor Pollutants on House Dust Mite Allergic Asthma

Aldehyde and Nitrogen Dioxide at Homes: Measurement of the Exposure and Their Role on Allergic Asthma

It seems that the aldehydes and NO2, at the levels found indoor, could be the aggravating factors for an allergic response. However this effect has not been demonstrated. The investigators plan to study the effect of exposure to standard doses of these pollutants on the bronchial reactivity as measured by bronchial challenge tests with dust mite extract in volunteers asthmatic, allergic to house dust mite.

Inclusion criteria:

• M/F 18-50 years of age
• History of intermittent HDM allergic asthma-FEV1 > 80%
• Non smokers or smokers with smoking < 10 PY

Exclusion criteria:

• Persistent asthma and FEV1<80%
• Allergic to pets and pets at home