Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

Vyvanse and Glucose Intolerance in Children With ADHD and Obesity

The purpose of this study to assess the effects of chronic administration of Vyvanse (lis-dexamphetamine) on glucose metabolism in a sample of children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) who also have glucose intolerance and are obese.

Inclusion Criteria:

• male or female, ages between 8 and 17
• Body Mass Index > 30
• fasting blood sugar between 90-100 mg/dl
• 2 hour post prandial >140 <180 mg/dl
• meets criteria for a diagnosis of ADHD, any subtype

Exclusion Criteria:

• known cardiovascular disease or diabetes
• structural cardiac abnormalities, abnormal ECGs, family history of sudden death
• positive urine drug screen
• fasting blood sugar level > 126 mg/dl
• HbA1c > 6.5 %
• Weight > 300 lbs