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| Name | Class |
|---|---|
| University of Parma | OTHER |
| IRCCS Fondazione Stella Maris | OTHER |
Evidence exists that the activation of actions activates the same cortical motor areas that are involved in the performance of the observed actions. The neural substrate for this phenomena is the mirror neuron system. It is generally assumed that mirror neurons have a basic role in understanding the intentions of others and in imitation learning. There is evidence that action observation has a positive effect on rehabilitation of motor disorders after stroke. The aim of this study is to demonstrate that action observation followed by the repetition of the actions previously observed has a positive impact on rehabilitation of the upper limb in children affected by hemiplegia as a consequence of Cerebral Palsy. In particular, the purpose is to assess if mirror neurons could improve the amount, the quality and the velocity of movements and the cooperation between the two upper extremities.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Action observation plus repetition | Experimental | Observation of actions and repetition of the same actions |
|
| repetition only | Active Comparator | repetition of gestures |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| action observation therapy | Other | 15 consecutive sessions of 18 minutes, plus repetition |
|
| Measure | Description | Time Frame |
|---|---|---|
| Melbourne Assessment of unilateral limb function | T0=baseline, Tend (week three) , T2(two months) T6months (six months after the completion of the training) |
| Measure | Description | Time Frame |
|---|---|---|
| Assisting Hand Assessment | T0, Tend, T2, T6 | |
| Jebsen-Taylor | T0, Tend, T2, T6 | |
| Abilhand emikids |
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rizzolatti Giacomo, Professor | University of Parma | Principal Investigator |
| Ferrari Adriano, Professor | University of Modena and Reggio Emilia | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital of Parma | Parma | Parma | 43100 | Italy | ||
| IRCCS Stella Maris |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32986904 | Derived | Sgandurra G, Biagi L, Fogassi L, Ferrari A, Sicola E, Guzzetta A, Tosetti M, Cioni G. Reorganization of action observation and sensory-motor networks after action observation therapy in children with congenital hemiplegia: A pilot study. Dev Neurobiol. 2020 Sep;80(9-10):351-360. doi: 10.1002/dneu.22783. Epub 2020 Oct 28. | |
| 21711525 |
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| ID | Term |
|---|---|
| D006429 | Hemiplegia |
| D002547 | Cerebral Palsy |
| ID | Term |
|---|---|
| D010243 | Paralysis |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| repetition of gestures | Other | 15 consecutive session of visual games, plus repetition of gestures |
|
| T0, Tend, T2, T6 |
| Pisa |
| Pisa |
| Italy |
| Azienda Santa Maria Nuova - | Reggio Emilia | Reggio Emilia | 42100 | Italy |
| Sgandurra G, Ferrari A, Cossu G, Guzzetta A, Biagi L, Tosetti M, Fogassi L, Cioni G. Upper limb children action-observation training (UP-CAT): a randomised controlled trial in hemiplegic cerebral palsy. BMC Neurol. 2011 Jun 28;11:80. doi: 10.1186/1471-2377-11-80. |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D001925 | Brain Damage, Chronic |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |