Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae

FIST-MC-09 Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae

The investigators will study whether local instillation of Doxycycline and Acetylcystein results in fistula closure in CD patients.

Inclusion criteria:

• fistulizing CD
• CD < 6 months
• at least one insufficient fistula closure try

Exclusion criteria:

• CDAI > 200
• Abscesses
• CRP > 100