Trial for the Treatment of Acute Asthma in Wheezy Pre-school Aged Children

A Double Blind Randomized Control Trail of Azithromycin for the Acute Management of Wheezy Pre-school Children

To determine if treatment of pre-school children with a history of wheeze who present to an Emergency Department with an acute wheezing episode with azithromycin for 5 days will resolve their symptoms more quickly, will require less short acting beta agonist (SABA), and allow these children to remain symptom free for a longer period of time.

Inclusion Criteria:

• 12-60 months
• wheeze on auscultation

Exclusion Criteria:

• antibiotic use in the past 30 days
• macrolide allergy
• underlying medical condition
• significant co-morbidities
• current enrollment
• language barrier or no access to phone for follow up