Gonadal Toxicity in Women With Hodgkin Lymphoma

Observational Retrospective Study to Evaluate the Incidence of the Gonadal Toxicity in Women of Reproductive Age With Hodgkin Lymphoma

The Gruppo Italiano Studio Linfomi has been collecting data on patients with Hodgkin Lymphoma (HL) since 1988. This archive represents a homogeneous series of consecutive patients with HL. The very long follow up and the availability of clinical and treatment data make it feasible to perform a study on the gonadal toxicity related to treatment for HL.

Inclusion Criteria:

• Female patients in complete remission after chemotherapy for Hodgkin lymphoma
• Age ≥ 18 e < 40 years
• Previous regular menstrual cycle
• No previous or concomitant gynecological diseases affecting reproducing function
• No other chemo-radiotherapy for other neoplasm
• Written informed consent

Exclusion Criteria:

• none