Antibiotic Therapy of Acute Uncomplicated Colonic Diverticulitis

Is Antibiotic Therapy Mandatory for Treatment of Uncomplicated Acute Colonic Diverticulitis: a Randomized Clinical Trial

The purpose of this study is to evaluate if antibiotic therapy is necessary for treatment of uncomplicated colonic diverticulitis.

The hypothesis is that Patients with acute uncomplicated colonic diverticulitis will recover the condition without antibiotic therapy and the lack of antibiotic therapy will not lead to complications.

The patients will be randomized to conservative treatment with and without antibiotic therapy.

Inclusion Criteria:

• adults with CT sign of acute colonic uncomplicated diverticulitis
• elevated CRP and LPK
• Temp.38c or more

Exclusion Criteria:

• patients with peritonitis, sepsis or CT- sign of complicated diverticulitis with abscesses or free abdominal air
• pregnancy
• immunological incompetence and immunosuppressive therapy