The purpose of this study is to evaluate with sufficient precision and according to gender the determining independent factors of quality of life related to respiratory status of patient with moderate to severe COPD.

Inclusion Criteria:

• Adult patient who has a clinical visit for their usual follow-up.
• patient with COPD with at least a three month follow up

Exclusion Criteria:

• Current or history of asthma
• Current participation in an interventional clinical study

First 3 consecutive adults with COPD with at least a three month follow up, seen by pneumologist