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| Name | Class |
|---|---|
| RAND | OTHER |
| Vanderbilt University | OTHER |
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Trained para-professional health care workers will implement a stepped-care model of depression care in commune health stations in Vietnam.
This project focuses on evaluation of a collaborative care system for treatment of depression in Vietnam. This system involves training para-professional health care workers in a stepped-care model system of depression care to be implemented in commune health stations in Vietnam.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Guideline Antidepressant Medication | Active Comparator | Guideline Antidepressant Medication, following the VN National Mental Health plan. |
|
| Behavioral Activation + Medication | Experimental | Psychoeducation, behavioral activation therapy, and medication delivered within a collaborative care model. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Behavioral Activation + Medication | Other | Psychoeducation, behavioral activation therapy, and medication delivered within a collaborative care model. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change across time (random effects slope) in depressive symptoms, as assessed by the PHQ-9 questionnaire | The PHQ-9 (Patient Health Questionnaire-9) assesses depressive symptoms, over the last two weeks. It is assessed at 0, 6, 12, 24 weeks. The outcome target is the linear and quadratic change slopes across these 4 time points. | 0, 6, 12, 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change across time (random effects slope) in anxiety symptoms, as assessed by the GAD-7 questionnaire | The GAD-7 (General Anxiety Disorder-7) assesses anxiety symptoms, over the last two weeks. It is assessed at 0, 6, 12, 24 weeks. The outcome target is the linear and quadratic change slopes across these 4 time points. | 0, 6, 12, 24 weeks |
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Inclusion Criteria:
Exclusion Criteria: active psychosis, mania, substance abuse, suicidal behaviors, cognitive impairment.
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| Name | Affiliation | Role |
|---|---|---|
| victoria ngo, phd | RAND | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Khanh Hoa Provincial Hospital | Nha Trang | Khanh Hoa | Vietnam | |||
| Danang Psychiatric Hospital |
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| ID | Term |
|---|---|
| D003863 | Depression |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D004304 | Dosage Forms |
| D017367 | Selective Serotonin Reuptake Inhibitors |
| ID | Term |
|---|---|
| D004364 | Pharmaceutical Preparations |
| D013678 | Technology, Pharmaceutical |
| D008919 | Investigative Techniques |
| D014179 | Neurotransmitter Uptake Inhibitors |
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|
| Guideline Antidepressant Medication | Drug | Guideline Antidepressant Medication, following the VN National Mental Health plan. |
|
| Change across time (random effects slope) in physical health, as assessed by the SF-12 questionnaire, Physical Health subscale |
The SF-12 questionnaire, Physical Health subscale, assesses physical health functioning. It is assessed at 0, 6, 12, 24 weeks. The outcome target is the linear and quadratic change slopes across these 4 time points. |
| 0, 6, 12, 24 weeks |
| Change across time (random effects slope) in mental health, as assessed by the SF-12 questionnaire, Mental Health subscale | The SF-12 questionnaire, Mental Health subscale, assesses mental health functioning. It is assessed at 0, 6, 12, 24 weeks. The outcome target is the linear and quadratic change slopes across these 4 time points. | 0, 6, 12, 24 weeks |
| Change across time (random effects slope) in behavioral activation skills and behaviors, as assessed by the BADS questionnaire. | The BADS (Behavioral Activation for Depression Scale) questionnaire assesses behavioral activation-related skills and behaviors. It is assessed at 0, 6, 12, 24 weeks. The outcome target is the linear and quadratic change slopes across these 4 time points. | 0, 6, 12, 24 weeks |
| "Substantial improvement" in depressive symptoms, as assessed by the PHQ-9 | Rates of substantial symptomatic improvement (50% or greater reduction in PHQ-9 scores from baseline), to (a) 6 weeks, (b) 12 weeks, (c) 24 weeks. | 6, 12, 24 weeks |
| "Depression remission", as assessed by the PHQ-9 | Depression remission (PHQ-9<5), at (a) 6 weeks, (b) 12 weeks, (c) 24 weeks. | 6, 12, 24 weeks |
| Da Nang |
| Vietnam |
| D049990 | Membrane Transport Modulators |
| D045504 | Molecular Mechanisms of Pharmacological Action |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D018377 | Neurotransmitter Agents |
| D018490 | Serotonin Agents |
| D045505 | Physiological Effects of Drugs |