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The purpose of the study is to evaluate the outcome of treatment switch defined as an improvement in CGI-CB scale (Clinical Global Impression - Clinical Benefit).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Antipsychotic outpatients with schizophrenia | Switched treatment of antipsychotic outpatients with schizophrenia |
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| Measure | Description | Time Frame |
|---|---|---|
| CGI-CB scale score of subjects achieving a score of < 4. | At Week 18 - once |
| Measure | Description | Time Frame |
|---|---|---|
| Change in PANSS scale | Baseline (Day 0) to the end of study treatment (week 6, week 12, week 18) or the premature study withdrawal of the subject - up to 4 times in 18 weeks | |
| Change in BARS scale | Baseline (Day 0) to the end of study treatment (week 6, week 12, week 18) or the premature study withdrawal of the subject - up to 4 times in 18 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects who have undergone a switch in their antipsychotic treatment and fulfill the following criteria will participate in the study.
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| Name | Affiliation | Role |
|---|---|---|
| Panagiotis Pontikis, Dr. | Marketing Company Medical and Regulatory Affairs Director, AstraZeneca S.A. Greece | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Site | Pátrai | Achaias | Greece | |||
| Research Site |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24359635 | Derived | Roussidis A, Kalkavoura C, Dimelis D, Theodorou A, Ioannidou I, Mellos E, Mylonaki T, Spyropoulou A, Yfantis A. Reasons and clinical outcomes of antipsychotic treatment switch in outpatients with schizophrenia in real-life clinical settings: the ETOS observational study. Ann Gen Psychiatry. 2013 Dec 20;12(1):42. doi: 10.1186/1744-859X-12-42. |
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| Changes in CGI-S and CGI-I scales | Baseline (Day 0) to the end of study treatment (week 6, week 12, week 18) or the premature study withdrawal of the subject - up to 4 times in 18 weeks |
| Nafplion |
| Argolidas |
| Greece |
| Research Site | Tripoli | Arkadias | Greece |
| Research Site | Athens | Attica | Greece |
| Research Site | Dafni | Attica | Greece |
| Research Site | Drapetsona | Attica | Greece |
| Research Site | Exarcheia | Attica | Greece |
| Research Site | Glifada | Attica | Greece |
| Research Site | Ilioúpoli | Attica | Greece |
| Research Site | Ilissia | Attica | Greece |
| Research Site | Koridalos | Attica | Greece |
| Research Site | Marousi | Attica | Greece |
| Research Site | N. Makri | Attica | Greece |
| Research Site | P. Faliro | Attica | Greece |
| Research Site | Pangrati | Attica | Greece |
| Research Site | Peristeri | Attica | Greece |
| Research Site | Petroúpolis | Attica | Greece |
| Research Site | Piraeus | Attica | Greece |
| Research Site | Zografos | Attica | Greece |
| Research Site | Athens | Attikis | Greece |
| Research Site | Koropí | Attikis | Greece |
| Research Site | Néo Irákleio | Attikis | Greece |
| Research Site | Chania | Chanion | Greece |
| Research Site | Kos | Dodekanissou | Greece |
| Research Site | Corfu | Eptanisa | Greece |
| Research Site | Agrinio | Etoloakarnanias | Greece |
| Research Site | Alexandroupoli | Evrou | Greece |
| Research Site | Lamia | Fthiotidos | Greece |
| Research Site | Heraklio | Herakliou | Greece |
| Research Site | Véroia | Imatheias | Greece |
| Research Site | Ioannina | Ioanninon | Greece |
| Research Site | Karditsa | Karditsas | Greece |
| Research Site | Kavala | Kavalas | Greece |
| Research Site | Larissa | Larissas | Greece |
| Research Site | Volos | Magnisias | Greece |
| Research Site | Kalamata | Mesinias | Greece |
| Research Site | Giannitsá | Pellas | Greece |
| Research Site | Rethymno | Rethimnou | Greece |
| Research Site | Komotini | Rodopis | Greece |
| Research Site | Serres | Serres | Greece |
| Research Site | Thessaloniki | Thessalonikis | Greece |
| Research Site | Trikala | Trikalon | Greece |
| Research Site | Thebes | Viotias | Greece |
| ID | Term |
|---|---|
| D012559 | Schizophrenia |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
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