The objective of this Post Marketing Surveillance (PMS) is to gain information about safety and efficacy in real practice.

Inclusion Criteria:

• Healthy female subjects

  • requesting contraception
  • suggesting PMDD by Physician who are also requesting contraception
  • with acne who are also requesting contraception

• Age: 18 - 50 years

• Women who is prescribed YAZ first, during study period

Exclusion Criteria:

• Women who are contraindicated based on the label of YAZ

  • Presence or a history of venous or arterial thrombotic/ thromboembolic events (e.g. deep venous thrombosis, pulmonary embolism, myocardial infarction) or of a cerebrovascular accident
  • Presence or history of prodromi of a thrombosis (e.g. transient ischaemic attack, angina pectoris)
  • History of migraine with focal neurological symptoms
  • Diabetes mellitus with vascular involvement
  • The presence of a severe or multiple risk factor(s) for venous or arterial thrombosis may also constitute a contraindication
  • Pancreatitis or a history thereof if associated with severe hypertriglyceridemia
  • Presence or history of severe hepatic disease as long as liver function values have not returned to normal
  • Severe renal insufficiency or acute renal failure
  • Presence or history of liver tumours (benign or malignant)
  • Known or suspected sex-steroid influenced malignancies (e.g. of the genital organs or the breasts)
  • Undiagnosed vaginal bleeding
  • Known or suspected pregnancy
  • Hypersensitivity to the active substances or to any of the excipients

Korean female who need only contraception or contraception and management of PMDD or contraception and treatment of acne.