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The present project is aimed at determining the prevalence of LDL-C <130 mg/dl with hsCRP ≥2mg/l, and of HDL-C < 40 mg/dl in Spain together with the estimation of cardiovascular risk, to analyze the contribution of measuring hsCRP for primary prevention purposes. In a subgroup of that population a number of inflammatory and oxidative status biomarkers would be also measured to better understand the meaning of elevated hsCRP.The study aim to analyze data already collected in studies (11 studies will participate) carried out in Spain, in 10 Spanish regions, after the year 2000.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Data from epidemiological studies performed after the year 2000 with patients between 35 and 74 years old |
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| Measure | Description | Time Frame |
|---|---|---|
| Lipid fractions: high-density lipoprotein, low-density lipoprotein, and total cholesterol, and triglycerides, and dislipidemia treatments | retrospectively |
| Measure | Description | Time Frame |
|---|---|---|
| High sensitivity C reactive protein & CHR risk by Framingham adapted functions | retrospectively | |
| Lipid profile among the Spanish regions, as in the primary outcome variable | retrospectively | |
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Inclusion Criteria:
Exclusion Criteria:
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Data from epidemiological studies performed after the year 2000 with patients between 35 and 74 years old
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Site | Andalucia | Andalusia | Spain | |||
| Research Site |
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No samples will be obtained, but biomarkers will be analysed from frozen serum samples retained by the pervious studies performed.
| Biomarkers: Interleukines 6 and 10, oxidized LDL, VCAM, ICAM, TNF alpha, neopterin, fibrinogen, lp(a), MMP 9 Apo A, Apo B, adiponectin, leptin, resistin, and yet other |
| prospectively |
| Canarias |
| Canary Islands |
| Spain |
| Research Site | Castilla Y Leon | Castille and León | Spain |
| Research Site | Talavero | Castille-La Mancha | Spain |
| Research Site | Girona | Catalonia | Spain |
| Research Site | Hospitalet | Catalonia | Spain |
| Research Site | Badajoz | Extremadura | Spain |
| Research Site | Madrid | Madrid | Spain |
| Research Site | Mallorca | Mallorca | Spain |
| Research Site | Murcia | Murcia | Spain |
| Research Site | Navarra | Navarre | Spain |