Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation

Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation in the Emergency Department

This is a clinical trial of propofol and alfentanil as agents for moderated procedural sedation in patients undergoing sedation in the emergency department (ED).

This was initially going to be a trial of propofol vs alfentanil vs nitrous oxide, but our use of nitrous oxide was discontinued before the trial began and the trial was conducted with only two arms

Inclusion Criteria:

• Adults undergoing moderate procedural sedation in the Emergency Department

Exclusion Criteria:

• Age <18 years
• Pregnancy
• Intoxication
• Cannot give informed consent
• Allergy to any of the three study medications
• ASA physical status score > 2
• Patients who require deep procedural sedation