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A retrospective analysis on a cohort of unselected COPD patients admitted to pulmonary rehabilitation (PR) performed in one rehabilitation centre has shown that the usual program is feasible and effective even in the presence of complex comorbidities, although some combined diseases might reduce the overall proportion of patients who respond to pre-defined outcomes criteria (Crisafulli E, et al. Thorax 2008;63:487-92).
The aim of this prospective study is to describe the pattern of prevalence of the most frequently associated COPD-comorbidities and the clinical impact on rehabilitation outcomes, referred to 3 teaching and 1 private hospitals admitting for pulmonary rehabilitation purposes.
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| Measure | Description | Time Frame |
|---|---|---|
| Nr. patients with a minimum clinically important difference (MCID) in quality of life (change in St George's Respiratory Questionnaire) | T0 (admission in hospital) - Tend (discharge, after 20 days) | |
| Nr. patients with a minimum clinically important difference (MCID) in exercise tolerance (change in 6MWD) | T0 (admission in hospital) - Tend (discharge, after 20 days) | |
| Nr. patients with a minimum clinically important difference (MCID) in breathless (change in MRC scale) | T0 (admission in hospital) - Tend (discharge, after 20 days) |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients who withdrew from rehabilitation. | Tend (discharge, after 20 days) | |
| Prevalence of comorbidities associated to COPD | Tend (discharge, after 20 days) |
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Inclusion Criteria:
Exclusion Criteria:
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COPD outpatients eligible for pulmonary rehabilitation
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| Name | Affiliation | Role |
|---|---|---|
| Enrico M Clini, Prof. | Villa Pineta Hospital and University of Modena | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Villa Pineta Hospital - University of Modena | Pavullo nel Frignano | Modena | 41026 | Italy | ||
| Clinic Center Private Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18203818 | Result | Crisafulli E, Costi S, Luppi F, Cirelli G, Cilione C, Coletti O, Fabbri LM, Clini EM. Role of comorbidities in a cohort of patients with COPD undergoing pulmonary rehabilitation. Thorax. 2008 Jun;63(6):487-92. doi: 10.1136/thx.2007.086371. Epub 2008 Jan 18. | |
| 20413540 | Derived | Crisafulli E, Gorgone P, Vagaggini B, Pagani M, Rossi G, Costa F, Guarriello V, Paggiaro P, Chetta A, de Blasio F, Olivieri D, Fabbri LM, Clini EM. Efficacy of standard rehabilitation in COPD outpatients with comorbidities. Eur Respir J. 2010 Nov;36(5):1042-8. doi: 10.1183/09031936.00203809. Epub 2010 Apr 22. |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| Naples |
| Italy |
| Dpt.of Clinical Sciences - University of Parma | Parma | Italy |
| Cardio-Thoracic Dpt - University of Pisa - | Pisa | Italy |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |