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This study aims to identify and quantify the factors associated with excess weight gain following treatment for breast cancer. It is believed that breast cancer patients gain more than 4% of their weight at diagnosis which is likely accompanied by an increase in body fat and waist circumference. It is further thought that this excess weight and increase in body fat and waist circumference are associated to tumour characteristics, chemotherapy, menopause status at diagnosis and the presence of genes related to obesity. It is also thought that women treated with chemotherapy have higher levels of glucose and insulin.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Breast cancer | Diagnosed with breast cancer 1/1/2003 - 31/12/2007. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fasting blood sample. | Procedure | Fasting blood sample taken following informed consent for genotyping, glucose and insulin levels. |
|
| Measure | Description | Time Frame |
|---|---|---|
| To provide evidence of the relationship between weight gain following diagnosis of breast cancer and tumour characteristics, chemotherapy, menopause status at diagnosis and the presence of genes related to obesity. | 12-18 months. |
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Inclusion Criteria:
Exclusion Criteria:
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Females over 18 years diagnosed with breast cancer between 1/1/2003 and 31/12/2007.
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| Name | Affiliation | Role |
|---|---|---|
| Tamas Hickish | Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust | Principal Investigator |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| D015430 | Weight Gain |
| D001835 | Body Weight |
| D009369 | Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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Fasting blood sample to determine participants genotype, insulin and glucose levels.
| D001836 |
| Body Weight Changes |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |