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The purpose of this study was to evaluate the relative bioavailability of Paddock Laboratories, Inc.'s test formulation of Moexipril/ Hydrochlorothiazide 15mg/25mg tablets with a reference formulation Uniretic®(Moexipril/ Hydrochlorothiazide) 15mg/25mg tablets, under fasting conditions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Moexipril HCl/ Hydrochlorothiazide 15mg/25mg Tablets | Experimental |
| |
| Uniretic® 15mg/25mg Tablets | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Moexipril HCl/ Hydrochlorothiazide 15mg/ 25mg Tablet, Paddock Laboratories, Inc. | Drug | test drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Bioequivalence specified outcomes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kennedy, M.D. | Novum Pharmaceutical Research Services | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Novum Pharmaceutical Research Services | Pittsburgh | Pennsylvania | 15206 | United States |
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| Uniretic® 15mg/25mg Tablets | Drug | reference drug |
|
| ID | Term |
|---|---|
| C058302 | moexipril |
| D006852 | Hydrochlorothiazide |
| D013607 | Tablets |
| ID | Term |
|---|---|
| D002740 | Chlorothiazide |
| D001581 | Benzothiadiazines |
| D013449 | Sulfonamides |
| D013450 | Sulfones |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
| D049971 | Thiazides |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
| D004304 | Dosage Forms |
| D004364 | Pharmaceutical Preparations |
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