Preoperative Methylprednisolone in Endovascular Aortic Repair

Preoperative Methylprednisolone in Endovascular Aortic Repair - a Randomized Double Blind Placebo Controlled Clinical Trial

The purpose of this study is to attenuate the systemic inflammatory response after Endovascular repair of abdominal aortic aneurysms, by administration of a single preoperative dosage of Methylprednisolone.

Inclusion Criteria:

• Elective endovascular repair of an asymptomatic abdominal aortic aneurysm.
• Informed signed consent

Exclusion Criteria:

• Positive HIV status, positive hepatitis B or C status
• Immunoinflammatory disease - except topically treated skin disease and respiratory disease.
• Glaucoma
• Gastric or duodenal ulcer
• Systemic fungal infection
• Immunosuppressive treatment
• Current treatment for cancer
• Allergy towards contents of Solu-Medrol
• Alcohol consumption: Men > 21 drinks and women > 14 drinks weekly
• Pregnancy
• Lack of informed signed consent
• Patients where follow up is planned at other location than Rigshospitalet.