Study of DE-105 Ophthalmic Solution in Patients With Persistent Corneal Epithelial Defect

Study of DE-105 Ophthalmic Solution in Patients With Persistent Corneal Epithelial Defect

Safety and efficacy of DE-105 ophthalmic solution in patients with persistent corneal epithelial defect will be evaluated. Dose-dependent efficacy will be evaluated as well.

Inclusion Criteria:

• Has corneal epithelial defect and decreased corneal sensitivity.
• Has undergone continuous treatment for corneal epithelial defect for 1 week or longer.

Exclusion Criteria:

• Presence of disease such as active ocular infection, or abnormal lid closure.
• History or presence of chemical burn, Stevens - Johnson Syndrome, etc.
• History of corneal transplantation, LASIK, or hematopoietic stem cell transplantation.