This is a clinical trial to compare the benefits and possible adverse events of two antibiotic treatments for mild to moderate acne. It is expected that minocycline microgranules will be more effective than lymecycline with a better adverse events profile.

Inclusion Criteria:

• Both gender
• 14 to 30 years old
• Mild to moderate acne
• Face localization
• At least 20 non-inflammatory lesions OR
• At least 15 inflammatory lesions OR
• At least 30 total lesions AND
• Less than 5 nodular lesions

Exclusion Criteria:

• Patients younger than 14 or older than 30 years old
• Less than 20 non-inflammatory lesions OR
• Less than 15 inflammatory lesions OR
• Less than 30 total lesions
• Patients with severe acne
• More than 5 nodular lesions OR
• More than 50 inflammatory lesions OR
• More than 125 total lesions
• Pregnant women
• Lactating women