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At least 60% of patients with constipation and dyssynergic defecation (anismus) and between 30-50% of patients with fecal incontinence exhibit impaired rectal sensation. The problem may be improved by biofeedback therapy. Traditionally, biofeedback therapy was performed by using a syringe-assisted technique. Although some respond to this method, many, particularly those with severe rectal hyposensitivity have proved to be refractory. Also, repeated inflation and deflation of a large volume of air, using a hand-held syringe is cumbersome and time consuming. Recently, in pilot observations, the investigators have seen that a barostat-assisted technique of biofeedback therapy was simpler and easier to perform and could possibly be more effective. The investigators' aims are:
When compared to those who receive syringe-assisted training, patients receiving barostat training will demonstrate:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Syringe Conditioning | Active Comparator | A syringe will be used to inflate the balloon at the end of the probe which is inside of the rectum. |
|
| Barostat Conditioning | Experimental | A barostat machine will be used to inflate the balloon at the end of the probe which is inside of the rectum. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Syringe Conditioning | Procedure | A syringe will be used to inflate the balloon at the end of the probe which is inside of the rectum. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Rectal Sensory Thresholds | Trial entry and at the end of 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Satisfaction with bowel function based on Visual Analog Scale (VAS) | Trial Entry and at the end of 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Satish Rao, Md, PhD | University of Iowa | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | United States |
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| ID | Term |
|---|---|
| D003248 | Constipation |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D013594 | Syringes |
| ID | Term |
|---|---|
| D004864 | Equipment and Supplies |
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| Barostat Conditioning | Procedure | A barostat machine will be used to inflate the balloon at the end of the probe which is inside of the rectum. |
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