EBUS-guided TBNA for Molecular Diagnostic of Mediastinal Lymph Nodes (LN)

EBUS-guided TBNA for Molecular Diagnostic of Mediastinal Lymph Nodes

The purpose of this study is to perform molecular diagnostic in mediastinal lymph nodes of non-small cell lung cancer patients sampled by endobronchial ultrasound guided finde needle aspiration (EBUS-TBNA).

NSCLC is a common cancer. Accurate and early staging has a significant impact on outcome. EBUS-TBNA of involved mediastinal lymph nodes is critical. Molecular markers could improve mediastinal staging.

Inclusion Criteria:

• Age ≥ 18 years
• Samples are collected before surgery or before any therapy
• ECOG 0 or 1
• Clinical stage I-II, T1-2, N0-1, M0)
• Surgically respectable
• Patient with enlarged med. lymphnodes (control group)

Exclusion Criteria:

• Previous RT/CHT
• Previous or current cancer of other entity