Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis

The purpose of this study is to examine safety and efficacy of Patanase and Astelin in treating the symptoms of non-allergic vasomotor rhinitis (VMR).

Inclusion Criteria:

• Diagnosis of VMR with at least 2 years of chronic non-allergic rhinitis
• Negative skin tests to a panel of allergens and positive histamine test within last 2 years
• History of symptoms related to defined VMR triggers

Exclusion Criteria:

• Nasal disorder, surgery, or concurrent disease that could interfere with evaluation of study medications
• Bacterial or viral infection within 14 days of first visit. Diagnosis of acute sinusitis within 30 days of first visit
• Chronic use of drugs that can cause rhinitis