Necrotizing Enterocolitis (Nec) and B. Lactis in Premature Babies

Prevention of NEC in Preterm Infants With B. Lactis

The purpose of the trial is to demonstrate the effect of B. lactis in reducing the incidence of Necrotizing Enterocolitis (NEC) compared to placebo in preterm infants.

Inclusion Criteria:

• Weight between 800 - 1500g
• Tolerating enteral feeding within 48 hours
• Having obtained his/her parents or legal representative informed consent

Exclusion Criteria:

• Chromosomal abnormality
• Hydrops featalis
• Congenital malformation of the gastrointestinal tract
• Congenital heart defects or other major congenital abnormalities likely to affect feeding and/or feeding tolerance
• Currently participating in another clinical trial