Comparison Azathioprine to Mesalazine for the Prevention of Postoperative Recurrence in the Crohn Disease

A Multicentre Randomized Open Study Comparing Azathioprine to Mesalazine for the Prevention of Postoperative Recurrence in the Crohn Disease

To show the superiority of Azathioprine comparing Mesalazine in the prevention of postoperative recurrence in Crohn's Disease.

Inclusion Criteria:

• more than 18 years old
• Clinical remission at inclusion time (CDAI<150)
• Having ileocolonic or colon resection 21 days before inclusion
• Resection > 50cm or subtotal colectomy with ileorectal anastomosis

Exclusion Criteria:

• Intolerance to one of both study treatment
• Liver failure (TP<60%)
• Renal Failure (Creatinine < Lab results)