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Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth. The purpose of this study was to evaluate the effects of pistacia Mutica (PM) mouth wash on de novo dental plaque plaque formation, gingival inflammation indices and oral microorganisms.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| pistacia Mutica | Experimental | The subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days. |
|
| placebo | Placebo Comparator | The subjects were asked to use a mouthwash containing Placebo twice a day for 4 days. |
|
| Chlorhexidine | Active Comparator | The subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pistacia Mutica extract | Drug | The subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The effects of pistacia Mutica extract (PM) on de novo plaque formation. | In a 4 days experimental periods followed by a 10 days wash-out periods. |
| Measure | Description | Time Frame |
|---|---|---|
| staining effects of pistacia Mutica extract in comparison to placebo or Chlorhexidine | In a 4 days experimental periods followed by a 10 days wash-out periods |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Reza Pourabbas, DDS,MSD | Tabriz University of Medical Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Drug Applied Science Center, tabriz Univ. of Medical Sciences | Tabriz | East Azerbaijan Province | Iran |
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| ID | Term |
|---|---|
| D005891 | Gingivitis |
| D003773 | Dental Plaque |
| ID | Term |
|---|---|
| D007239 | Infections |
| D005882 | Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
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| ID | Term |
|---|---|
| D002710 | Chlorhexidine |
| ID | Term |
|---|---|
| D001645 | Biguanides |
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
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| Placebo | Drug | The subjects were asked to use a placebo mouthwash twice a day for 4 days. |
|
| Chlorhexidine | Drug | The subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days. |
|
| D009057 |
| Stomatognathic Diseases |
| D003741 | Dental Deposits |
| D014076 | Tooth Diseases |