The purpose of this study is to evaluate the safety and preliminary efficacy of two formulations of the Latanoprost-PPDS in subjects with ocular hypertension or open-angle glaucoma.

Inclusion Criteria:

• Subjects over 18 years of age diagnosed with ocular hypertension or open-angle glaucoma
• Subjects who have a best corrected visual acuity of 20/100 or better

Exclusion Criteria:

• Subjects who wear contact lenses
• Subjects who have uncontrolled medical conditions
• Subjects requiring chronic topical artificial tears, lubricants, and/or requiring any other chronic ocular topical medications
• Subjects who have a history of chronic or recurrent inflammatory eye disease