Study of Mitomycin C and Nasal Splint to Treat Nasal Synechiae

Comparative Study of Mitomycin C and Internal Nasal Septal Splint in the Treatment of Nasal Synechiae

This study evaluates whether Mitomycin C is an effective alternative to septal splints in the treatment of nasal synechiae.

Nasal synechiae is an important cause for the failure of many a nasal surgery. Septal splints have been widely used for the treatment of nasal synechiae, but are associated significant morbidity until removal. To the best of our knowledge there are no studies in literature comparing Mitomycin C with septal splints as an atraumatic alternative in the treatment of nasal synechiae. This is a preliminary study taken up to evaluate the therapeutic efficacy of Mitomycin C in the treatment of nasal synechiae.

Inclusion Criteria:

• Patients with nasal mucosal synechiae due to surgical or non-surgical trauma

Exclusion Criteria:

• Patients with nasal vestibular stenosis
• Patients with nasal synechiae due to diseases like Hansen's disease, Syphilis, Rhinoscleroma, Atrophic Rhinitis etc.