The study objective is to evaluate the effectiveness of Traditional Chinese Medicine (TCM) five elements music therapy improving quality of life for patients with advanced cancer, as well as establishing the standard operating procedures (SOP) for it.

Design: As randomized controlled trial (RCT) with un-blinded design will be done.

Inclusion Criteria:

• Eligible participation will be enrolled based on diagnostic criteria.
• Advanced cancer patient with more than 50 scores of Karnofsky Performance Score (KPS).
• Diagnosis of advanced cancer
• Patients who are willing to be subject with taking part in this research voluntarily.
• No prior experience with TCM music therapy.
• Newly admitted to TCM oncology department for 3 weeks treatment course.

Exclusion Criteria:

• Complicated diagnose or one who don't consistent with inclusion criteria.
• Patients suffering from psychosis or diagnosis, or psychiatric diagnoses (e.g., schizophrenia).
• Suffering from acute organ prostration or other condition of demanding to rescue，inability for accepting music therapy.
• One don't read or fill in diary owing to some causes, such as state of the art or acuity of vision
• One suffering from hearing disturbance
• Accepted TCM five elements music therapy in the past.