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The purpose of this study is to compare plaque burden in the coronary and carotid arteries 5 years after adjuvant radiotherapy in women with right sided breast cancer vs left sided breast cancer.
This study reviews case series of patients with a history of breast cancer treated with radiotherapy for at least five years. The study measures atherosclerosis by using coronary and carotid artery calcium scoring.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cardiac counseling | 10 left sided breast cancer patients 10 right sided breast cancer patients | ||
| coronary artery evaluation | 10 left sided breast cancer 10 right sided breast cancer |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants Analyzed for Coronary Calcium Burden by AGS | Number of participants who received a coronary calcium scan. | Year 5 Post-Initiation of Radiotherapy |
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Inclusion Criteria:
Exclusion Criteria:
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breast cancer patients after radiation treatment
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| Name | Affiliation | Role |
|---|---|---|
| Alexander Hindenburg, MD | Winthrop University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Winthrop University Hospital | Mineola | New York | 11501 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24093087 | Background | Chang M, Suh J, Kirtani V, Dobrescu A, Haas J, Zeldis S, Shayani S, Hindenburg AA. Coronary Calcium Scanning in Patients after Adjuvant Radiation for Early Breast Cancer and Ductal Carcinoma In situ. Front Oncol. 2013 Sep 25;3:253. doi: 10.3389/fonc.2013.00253. eCollection 2013. |
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| ID | Title | Description |
|---|---|---|
| FG000 | Coronary Artery Evaluation Left Side Breast Cancer | 9 left sided breast cancer |
| FG001 | Coronary Artery Evaluation Right Side Breast Cancer | 11 right sided breast cancer |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
Age 60 years or younger at time of radiatiion to chest wall. All subjects had radiation at least 5 years prior to enrollment. Patients with clinical symtoms of CAD were excluded.
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| ID | Title | Description |
|---|---|---|
| BG000 | Coronary Artery Evaluation Left Side Breast Cancer | 9 left sided breast cancer |
| BG001 | Coronary Artery Evaluation Right Side Breast Cancer | 11 right sided breast cancer |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Number of Participants Analyzed for Coronary Calcium Burden by AGS | Number of participants who received a coronary calcium scan. | Posted | Count of Participants | Participants | Year 5 Post-Initiation of Radiotherapy |
|
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Coronary Artery Evaluation | 9 left sided breast cancer 11right sided breast cancer |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Dr. Alexander Hindenburg | Winthrop-University Hospital, Division of Hematology and Oncology | 516-663-9500 | AHindenburg@winthrop.org |
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| ID | Term |
|---|---|
| D050197 | Atherosclerosis |
| ID | Term |
|---|---|
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| BG002 | Total | Total of all reporting groups |
| Participants |
|
| Sex: Female, Male | Count of Participants | Participants |
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| Participants |
|
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| 0 |
| 20 |
| 0 |
| 20 |
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