Vitamin D, Blood Pressure, Lipids, Infection and Depression

Vitamin D, Blood Pressure, Lipids, Infection and Depression

There are numerous indications for a relation between low serum levels of 25(OH)D and blood pressure, lipid levels, frequency of infections and tendency towards depression. Whether it is a causal relationship it is not known, and can best be studied with a vitamin D intervention. The investigators hypothesis is that supplementation with a high dose vitamin D (40.000 IU per week) will have a beneficial effect on these parameters.

Inclusion Criteria:

• men and women 30 - 75 years of age
• low serum 25(OH)D levels

Exclusion Criteria:

• diabetes
• other serious diseases
• hypercalcemia