A Study to Investigate the Process by Which ABT-614 is Absorbed, Distributed, Metabolized and Eliminated in Humans

The objective of this study is to determine the amount of ABT-614 in the cerebral spinal fluid and blood after administration of a single dose and after administration of daily doses for 14 days in healthy volunteers.

Inclusion Criteria:

• Healthy male subjects between 18 and 40 years of age

Exclusion Criteria:

• History of bleeding disorders or deep vein thrombosis (DVT)
• Previous gastrointestinal (GI) surgery or chronic GI disease
• History of spinal surgery
• History of significant, chronic low back pain
• History of frequent headaches