Gut Hormone Profiling in Obese Patients With Type 2 Diabetes (MK-0000-134)

Gut Hormone Profiling in Peripheral Blood After Bariatric Surgery in Obese Patients With Type 2 Diabetes

This study will examine changes in various gut-derived hormones in obese type 2 diabetic patients before and after elective bariatric surgery.

Inclusion Criteria:

• Documented type 2 diabetes with total disease duration ≤10 years
• BMI of at least 35 kg/m^2
• Patient is a surgical candidate for either RYGBP, GBS or vertical sleeve gastrectomy (VSG)

Exclusion Criteria:

• Any illness that might confound the results of the study or pose additional risk to the patient by participation
• History of stroke, seizures, or other major neurological disorder
• History of cancer
• Patient uses or has used any medication that can alter body weight
• Patient is unwilling or unable to follow study procedures