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| Name | Class |
|---|---|
| Dutch Digestive Diseases Foundation | OTHER |
| Commission of Applied Clinical Research (Commissie voor Klinisch Toegepast Onderzoek: CKTO). | UNKNOWN |
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The objective of this study was to compare the functional and surgical results of the J-pouch with those of the side-to-end anastomosis and their impact on quality of life.
Invalidating anorectal dysfunctions are common after restorative rectal surgery. Improvement of functional results by the technically more demanding J-pouch has been demonstrated in comparison with the straight coloanal anastomosis. In the present multicenter randomized trial we assessed whether the J-pouch is also superior to the side-to-end coloanal anastomosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| j-pouch coloanal anastomosis | Other | although a j-pouch coloanal anastomosis is a common type of anastomosis, a comparison with the side-to-end has not been made. |
|
| side-to-end coloanal anastomosis | Other | in the Netherlands, the side-to-end anastomosis is the standard procedure to perform an anastomosis in case of rectal resection. therefore, the side-to-end group was our control group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| j-pouch coloanal anastomosis | Procedure |
| ||
| side-to-end coloanal anastomosis |
| Measure | Description | Time Frame |
|---|---|---|
| Primary endpoint was the function of the neo-rectum as assessed by a validated functional outcome questionnaire at 4 months. | 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| Function of the neo-rectum as assessed by the functional outcome questionnaire | 12 months | |
| Surgical results | 4 and 12 months | |
| Quality of life |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Academic Medical Center | Amsterdam | 1105 AZ | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21831100 | Derived | Doeksen A, Bakx R, Vincent A, van Tets WF, Sprangers MA, Gerhards MF, Bemelman WA, van Lanschot JJ. J-pouch vs side-to-end coloanal anastomosis after preoperative radiotherapy and total mesorectal excision for rectal cancer: a multicentre randomized trial. Colorectal Dis. 2012 Jun;14(6):705-13. doi: 10.1111/j.1463-1318.2011.02725.x. |
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| Procedure |
|
| 4 and 12 months |
| ID | Term |
|---|---|
| D012004 | Rectal Neoplasms |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
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