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The utilization of paclitaxel-eluting coronary stents in small vessel diseases is effective in reducing both repeat revascularization and major adverse cardiac events within two year follow-up. To evaluate the procedural, short and long term clinical outcomes of the Taxus Liberte™ Paclitaxel-Eluting Coronary Stent in small coronary arteries of ≤ 2.5 mm in the reference vessel diameter.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 2.5mm Paclitaxel-eluting stent | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TAXUS Liberté paclitaxel-eluting coronary stent system | Device | diameter is 2.5mm |
|
| Measure | Description | Time Frame |
|---|---|---|
| Target lesion revascularization rate | within 9months |
| Measure | Description | Time Frame |
|---|---|---|
| Technical success | initial | |
| Target lesion revascularization rate | 12 months | |
| Target lesion revascularization rate |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kenya Nasu, MD | Toyohashi Heart Center | Principal Investigator |
| Yuji Oikawa, MD | Cardiovascular institute hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Japanese red cross nagoya daiichi hospital | Nagoya | Aichi-ken | 4538511 | Japan | ||
| Higashi Cardiovascular clinic |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19463387 | Background | Turco MA, Ormiston JA, Popma JJ, Hall JJ, Mann T, Cannon LA, Webster MW, Mishkel GJ, O'Shaughnessy CD, McGarry TF, Mandinov L, Dawkins KD, Baim DS. Reduced risk of restenosis in small vessels and reduced risk of myocardial infarction in long lesions with the new thin-strut TAXUS Liberte stent: 1-year results from the TAXUS ATLAS program. JACC Cardiovasc Interv. 2008 Dec;1(6):699-709. doi: 10.1016/j.jcin.2008.09.007. | |
| 17359218 |
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| 24 months |
| Target vessel revascularization rate | 12 months |
| Target vessel revascularization rate | 24 months |
| The rate of MACE including MI due to stent thrombosis | 12 months |
| The rate of MACE including MI due to stent thrombosis | 24 months |
| Toyohashi |
| Aichi-ken |
| 4400836 |
| Japan |
| Toyohashi Heart Center | Toyohashi | Aichi-ken | 4418530 | Japan |
| Kokura memorial hospital | Kitakyushu | Fukuoka | 8028555 | Japan |
| Hoshi general hospital | Kōriyama | Fukushima | 9638501 | Japan |
| Southen tohoku research institute for neuroscience | Kōriyama | Fukushima | 9638563 | Japan |
| Gunma prefectural cardiovascular center | Maebashi | Gunma | 3710004 | Japan |
| Asahikawa medical college hospital | Asahikawa | Hokkaido | 0788510 | Japan |
| Hakodate central general hospital | Hakodate | Hokkaido | Japan |
| Shinko kakogawa hospital | Kakogawa | Hyōgo | 6750115 | Japan |
| Okamoto general hospital | Uji | Kyoto | 6110025 | Japan |
| Miyagi cardiovascular and respiratory center | Kurihara | Miyagi | 9894513 | Japan |
| Rinku general medical center | Izumiōtsu | Osaka | 5988577 | Japan |
| Sakurabashi watanabe hospital | Osaka | Osaka | 5300001 | Japan |
| Shuwa general hospital | Kasukabe | Saitama | 3440035 | Japan |
| Kasukabe chuo general hospital | Kasukabe | Saitama | 3440063 | Japan |
| Kusatsu Heart Center | Kusatsu | Shiga | 5250014 | Japan |
| Ayase heart hospital | Adachi City | Tokyo | 1200006 | Japan |
| The cardiovascular institute hospital | Minato | Tokyo | 1060032 | Japan |
| Tokyo metropolitan police hospital | Naka | Tokyo | 1648541 | Japan |
| JR tokyo general hospital | Shibuya City | Tokyo | 1518528 | Japan |
| Tokyo medical university hospital | Shinjuku | Tokyo | 1600023 | Japan |
| Itabashi Chuo medical center | tabashi City | Tokyo | 1740051 | Japan |
| Background |
| Ahmed WH. Review of the TAXUS Liberte SR paclitaxel-eluting coronary stent. Expert Rev Med Devices. 2007 Mar;4(2):117-20. doi: 10.1586/17434440.4.2.117. |
| 17010786 | Background | Elezi S, Dibra A, Mehilli J, Pache J, Wessely R, Schomig A, Kastrati A. Vessel size and outcome after coronary drug-eluting stent placement: results from a large cohort of patients treated with sirolimus- or paclitaxel-eluting stents. J Am Coll Cardiol. 2006 Oct 3;48(7):1304-9. doi: 10.1016/j.jacc.2006.05.068. Epub 2006 Sep 12. |
| ID | Term |
|---|---|
| D060050 | Angina, Stable |
| D000789 | Angina, Unstable |
| ID | Term |
|---|---|
| D000787 | Angina Pectoris |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
| D002637 | Chest Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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