The purpose of this study is to determine how well tolerated and safe AZD5069 is at different dose levels in healthy male and/or females. The study will also investigate how quickly AZD5069 is absorbed into and cleared by the body.

Inclusion Criteria:

• Provision of signed and dated, written informed consent
• Healthy male or female (of non child bearing potential) caucasian subjects aged 18 to 65 years with suitable veins for cannulation or repeated venepuncture
• Body mass index of between 18 and 30 kg/m2 inclusive

Exclusion Criteria:

• Subjects must not have any clinically significant disease or disorder, which, in the opinion of the Investigator, may either put the subject at risk because of participation in the study, or influence the results, or the subjects ability to participate in the study
• Subjects must not have any history of gastrointestinal, liver or kidney disease, or any other condition known to interfere with how drugs are absorbed, used or eliminated by the body
• Subjects must not have had any significant illness or medical/surgical procedures or injuries with 4 weeks of administration of the investigational product