Safety, Pharmacokinetics and Pharmacodynamics Study of BMS-866949 in Healthy Subjects

Placebo-Controlled, Ascending Single-Dose Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-866949 in Healthy Subjects

The purpose of this study is to evaluate the safety profile, tolerability, pharmacokinetics and pharmacodynamics of ascending single doses of BMS-866949 in healthy subjects.

Inclusion Criteria:

• Healthy male 18-55
• Women not of child bearing potential, 18-55

Exclusion Criteria:

• History of or current treatment for psychiatric illnesses, substance abuse or dependence
• History of a clinically significant neurological disorder (e.g., history of stroke, head trauma, etc.)