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| Name | Class |
|---|---|
| Universität Duisburg-Essen | OTHER |
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Stress during surgery leads to significant increase in plasma catecholamine concentrations in surgeons, anesthesiologists, and patients.
Hypothesis: Resection of pheochromocytomas can lead to more than normal stress in surgeons and because of abrupt hemodynamic changes in patients as well in anesthesiologists. Measurements of catecholamine concentrations at baseline, prior to surgery during and after surgery, are to be performed to test this hypothesis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Surgeon | To detect the degree of intraoperative stress, venous blod will be drawn from one surgeon during 8 pheochromocytoma resections. | ||
| Anesthesiologist | To detect the degree of intraoperative stress, venous blood will be drawn from one anesthesiologist during 8 pheochromocytoma resections. | ||
| Patients with pheochromocytoma | Venous blood will be drawn from 8 patients with pheochromocytoma during tumor resection. |
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Inclusion Criteria: Patients with pheochromocytoma (Older than 18 years) -
Exclusion Criteria: Patients younger than 18 years. Conservative treatment.
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The population consists of 8 patients with pheochromocytoma scheduled for tumor resection, one surgeon (with the experience of more than 50 pheochromocytoma resections) and one anesthesiologist (with the experience of more than 50 pheochromocytoma resections).
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| Name | Affiliation | Role |
|---|---|---|
| Harald Groeben, M.D. | Kliniken Essen-Mitte | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Prof. Dr. Harald Groeben | Essen | 45136 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16498054 | Background | Unger N, Pitt C, Schmidt IL, Walz MK, Schmid KW, Philipp T, Mann K, Petersenn S. Diagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass. Eur J Endocrinol. 2006 Mar;154(3):409-17. doi: 10.1530/eje.1.02097. | |
| 8541435 | Background | Schuttler J, Westhofen P, Kania U, Ihmsen H, Kammerecker S, Hirner A. [Quantitative assessment of catecholamine secretion as a rational principle of anesthesia management in pheochromocytoma surgery]. Anasthesiol Intensivmed Notfallmed Schmerzther. 1995 Oct;30(6):341-9. doi: 10.1055/s-2007-996507. German. |
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Venous blood will be drawn from the surgeon, anesthesiologist and from 8 patients to determine plasma catecholamine concentrations. Only plasma will be used for measurements.