Effects of follow-on Formula Enriched on Short-chain Fructooligosaccharides (scFOS) on Immune Response in Healthy Infants

A Placebo-controlled, Double-blind Randomized Study to Evaluate the Efficacy of a follow-on Milk Formula Supplemented With Fructo-oligosaccharides on Immune Response in Healthy Infants

In this study the investigators hypothesized that the chronic intake of fructo-oligosaccharides would increase fecal immunoglobulin A (IgA) specific to poliovirus vaccination and bifidobacteria in infants.

Inclusion Criteria:

• infants aged of 4 months at randomization
• not breast-fed infants

Exclusion Criteria:

• infants suffering from a chronic or severe disease susceptible to interfere with one of the evaluation criteria
• infants suffering from a disease associated with gastro-intestinal disorder
• infants who have taken antibiotic during the 2 months preceding randomization