Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination

Efficacy Of The Bimatoprost/Timolol Fixed Combination In Patients Treated With Bimatoprost for Primary Open Angle Glaucoma, Exfoliation Glaucoma or Ocular Hypertension.

The purpose of this study is to examine the ocular hypotensive effect of Bimatoprost and the potential additional effect of the Bimatoprost/Timolol fixed combination in eyes with ocular hypertension, primary open angle glaucoma or exfoliation glaucoma.

Inclusion Criteria:

• Primary open angle glaucoma
• Exfoliation glaucoma
• Ocular hypertension

Exclusion Criteria:

• Younger than 18 years old
• Inability to understand and/or follow study requirements
• Women of childbearing potential not using reliable birth control, pregnant or lactating women
• History of chronic obstructive pulmonary disease, heart failure, 2nd or 3rd AV block
• Anticipated modification of treatment for systemic hypertension during the study period
• History of ocular herpes, corneal scarring, conventional or laser surgery or macular pathology
• History of allergy, poor tolerability or poor response to study medication
• Best corrected visual acuity less than 0.4
• Significant visual field defect (MD<15.0 dB)