Phase 3, Randomized, Open-label Study Of The Efficacy And Safety Of Pf-02341066 Versus Standard Of Care Chemotherapy (Pemetrexed Or Docetaxel) In Patients With Advanced Non-small Cell Lung Cancer (Nsclc) Harboring A Translocation Or Inversion Event Involving The Anaplastic Lymphoma Kinase (Alk) Gene Locus
Phase 3, Randomized, Open-label Study Of The Efficacy And Safety Of Pf-02341066 Versus Standard Of Care Chemotherapy (Pemetrexed Or Docetaxel) In Patients With Advanced Non-small Cell Lung Cancer (Nsclc) Harboring A Translocation Or Inversion Event Involving The Anaplastic Lymphoma Kinase (Alk) Gene Locus
This is a Phase 3 trial comparing the safety and anti-tumor activity of PF-02341066 versus pemetrexed or docetaxel in patients with advanced non-small cell lung cancer with specific gene profile involving the ALK gene after failure of one previous chemotherapy regimen that included one platinum drug.
Inclusion Criteria:
Exclusion Criteria:
Little Rock, Arkansas 72205, United States
Los Angeles, California 90095-6984, United States
Orange, California 92868-3298, United States
Santa Monica, California 90404, United States
Aurora, Colorado 80045, United States
New York, New York 10022, United States
Oneida, New York 13421, United States
Oswego, New York 13126, United States
Syracuse, New York 13210, United States
Chapel Hill, North Carolina 27514, United States
Chapel Hill, North Carolina 27514, United States
Columbus, Ohio 43210, United States
Hershey, Pennsylvania 17033-0850, United States
Philadelphia, Pennsylvania 19104, United States
East Melbourne, Victoria 3002, Australia
Porto Alegre, Rio Grande do Sul 90050-170, Brazil
SĆ£o Paulo, SĆ£o Paulo 01246-000, Brazil
Sofia, Bulgaria 1756, Bulgaria
Montreal, Quebec H2L 4M1, Canada
Essen, 45122, Germany
GroĆhansdorf, 22927, Germany
Heidelberg, 69126, Germany
München, 80336, Germany
Wiesbaden, 65199, Germany
Heraklion, Crete 71110, Greece
Eksochi, Thessaloniki 57010, Greece
Pokfulam, Hong Kong
Shatin, New Territories, Hong Kong
Debrecen, 4032, Hungary
Milan, 20132, Italy
Milan, 20162, Italy
Perugia, 06132, Italy
Osakasayama-shi, Osaka 589-8511, Japan
Sunto-gun, Shizuoka 411-8777, Japan
Chuo-ku, Tokyo 104-0045, Japan
Kazan', 420029, Russia
Moscow, 115478, Russia
Saint Petersburg, 197022, Russia
Saint-Peterburg, 197089, Russia
Sochi, 354057, Russia
Seoul, 135-710, South Korea
A CoruƱa, A CoruƱa 15006, Spain
L'Hospitalet de Llobregat, Barcelona 08907, Spain
Cheshire, SK8 2PX, United Kingdom