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| ID | Type | Description | Link |
|---|---|---|---|
| R21AT002796 | U.S. NIH Grant/Contract | View source | |
| R21AT002796-01A1 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Center for Complementary and Integrative Health (NCCIH) | NIH |
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The purpose of this study was to determine the effect of a manual therapy technique (neural mobilization) on measures of clinical pain and function, experimental pain sensitivity, and on the function of the median nerve in individuals with carpal tunnel syndrome. The investigators hypothesized that individuals receiving a neural mobilization technique known to directly stress the median nerve would demonstrate greater improvements in clinical pain and function, experimental pain sensitivity, and median nerve function than those receiving a sham technique.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| neural mobilization | Experimental | manual therapy technique known to directly stress the median nerve |
|
| sham neural mobilization | Placebo Comparator | manual therapy technique known to directly stress the median nerve without any stimulation. |
|
| Healthy Controls | Active Comparator | People without carpal tunnel syndrome for comparison |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| neural mobilization | Procedure | manual therapy technique known to directly stress the median nerve |
|
| Measure | Description | Time Frame |
|---|---|---|
| thermal and pressure pain sensitivity | immediate effect |
| Measure | Description | Time Frame |
|---|---|---|
| grip strength | 3 weeks | |
| wrist range of motion | 3 weeks | |
| clinical pain |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Steven Z George, PhD | University of Florida Department of Physical Therapy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Florida | Gainesville | Florida | 32611 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19801812 | Result | Bialosky JE, Bishop MD, Price DD, Robinson ME, Vincent KR, George SZ. A randomized sham-controlled trial of a neurodynamic technique in the treatment of carpal tunnel syndrome. J Orthop Sports Phys Ther. 2009 Oct;39(10):709-23. doi: 10.2519/jospt.2009.3117. | |
| 21764354 | Result | Bialosky JE, Bishop MD, Robinson ME, Price DD, George SZ. Heightened pain sensitivity in individuals with signs and symptoms of carpal tunnel syndrome and the relationship to clinical outcomes following a manual therapy intervention. Man Ther. 2011 Dec;16(6):602-8. doi: 10.1016/j.math.2011.06.003. Epub 2011 Jul 20. |
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| ID | Term |
|---|---|
| D002349 | Carpal Tunnel Syndrome |
| ID | Term |
|---|---|
| D020423 | Median Neuropathy |
| D020422 | Mononeuropathies |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
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| sham neural mobilization | Procedure | sham technique mimicking the neural mobilization which is not specific to the median nerve |
|
| healthy controls | Other | People without carpal tunnel syndrome for comparison |
|
| 3 weeks |
| self report of disability | 3 weeks |
| median nerve function | 3 weeks |
| 19027342 | Result | Bialosky JE, Bishop MD, Price DD, Robinson ME, George SZ. The mechanisms of manual therapy in the treatment of musculoskeletal pain: a comprehensive model. Man Ther. 2009 Oct;14(5):531-8. doi: 10.1016/j.math.2008.09.001. Epub 2008 Nov 21. |
| D009422 | Nervous System Diseases |
| D009408 | Nerve Compression Syndromes |
| D012090 | Cumulative Trauma Disorders |
| D013180 | Sprains and Strains |
| D014947 | Wounds and Injuries |