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Choroidal neovascularisation in age related macular degeneration is one of the major causes of legal blindness in the western world existing in two major occurences, the dry and the wet form.The etiology of age related macular degeneration is yet unknown. Genetic factors, oxidative stress, Ischaemia, and aging of the retinal pigment epithelium are discussed as etiologic factors. The risk of rapid vision loss is much higher in wet AMD, a dry form may transform to a wet form. From a prior study the investigators know that the posterior hyaloid is significantly more frequent attached in wet AMD. This study is conducted to examine whether the attached posterior hyaloid is a risk factor to develop wet AMD in dry AMD cases.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dry AMD | male or female persons aged over 50 years with dry age-related macular degeneration |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ultrasound | Device | A-scan and B-scan ultrasound at baseline and month 6,12,24 |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Number of eyes with non-exudative AMD with attached and detached posterior vitreous cortex developing exudative AMD | 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| Distance acuity | 24 months | |
| Age | 24 months | |
| Smoking |
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Inclusion Criteria:
Exclusion Criteria:
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male or female persons aged over 50 years with dry AMD
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ilse Krebs, MD | Contact | +43171165 | 4607 | ilse.krebs@wienkav.at |
| Name | Affiliation | Role |
|---|---|---|
| Susanne Binder, Prof MD | Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ludwig Boltzmann Institute for Retinology and Biomicroscopic Lasersurgery | Recruiting | Vienna | State of Vienna | 1030 | Austria |
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| OCT |
| Device |
Volume scans of spectralis OCT at baseline and month 6,12,24 |
|
| 24 months |
| Obesity | 24 months |
| Lesion classification (AREDS) | 24 months |
| ID | Term |
|---|---|
| D008268 | Macular Degeneration |
| ID | Term |
|---|---|
| D012162 | Retinal Degeneration |
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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