Effect of Rapeseed Oil and Sunflower Oil

Effect of a Diet With Rapeseed Oil /Sunflower Oil on Lipoprotein in Children and Adolescents With Familial Hypercholesterolemia

Familial hypercholesterolemia (FH), an inherited disorder of lipoprotein metabolism, is a risk for early cardiovascular disease (CVD). This autosomal dominant disease is characterized by markedly elevated plasma concentrations of low density lipoprotein (LDL) and total cholesterol (TC). The purpose of this study is to compare the effect of a diet low in saturated fats but enriched either with rapeseed oil (RO) or sunflower oil (SO) in children and adolescents with FH on serum lipoproteins.

Inclusion Criteria:

• chilren and adolescents between 6 and 18 years of age
• LDLc > 130 mg/dl and
• TC > 200 mg/dl
• 7 day nutrition record
• written informed consent

Exclusion Criteria:

• overweight
• underweight
• mental disability
• drug therapy